Company Profile

Legend Biotech USA

Company Overview

Legend Biotech is a global clinical-stage biopharmaceutical company engaged in the discovery and development of novel cell therapies for oncology and other indications. Our team of over 1,000 employees across the United States, China and Europe, along with our differentiated technology, global development, and manufacturing strategies and expertise, provide us with the strong potential to discover, develop, and manufacture cutting edge cell therapies for patients in need.

Company History

Legend Biotech was founded as an early-stage cell therapy company in 2014. The company was the brainchild of visionary scientists who recognized that antibody-based therapeutics could potentially treat disease and possessed the backgrounds in immunology and gene editing to take the leap.

For two years, Legend Biotech, then known as the “Legend Project,” operated in a room the size of a freight elevator, with the goal of creating a cell therapy for multiple myeloma, a hematological cancer that often relapses and can become refractory. The team produced nanobodies for single-domain antibody drugs and ultimately extended the half-life of the nanobodies with proprietary technologies.

In 2015, Legend’s scientists focused on research for chimeric antigen-receptor T-cells (CAR-T) targeting the BCMA protein, making the biotech one of the first companies in the world to engineer CAR-T cells for the BCMA protein. In 2016, investigator-initiated trials began in China.

In 2017, data from the trials were presented at the American Society for Clinical Oncology (ASCO), which led to a partnership with biopharmaceutical company Janssen Biotech, Inc. to co-develop the anti-BCMA CAR-T, ciltacabtagene autoleucel (cilta-cel). Applications seeking approval of cilta-cel for the treatment of patients with RRMM are currently under regulatory review by several health authorities around the world. CARVYKTI™ (ciltacabtagene autoleucel) was approved by the U.S. Food and Drug Administration in February 2022 and received conditional marketing approval from the European Medicines Agency in May 2022.

Today Legend Biotech is a global, commercial-stage company driven by a passion for patients. We continue to build our pipeline of cell therapy platforms, which includes CAR-T, CAR-NK, CAR-?? T and non-gene-editing CAR technologies.

Our goal is to bring hope and opportunity to patients and their families by continuing to explore unique technologies.

Positions Available
  • 1 day ago

    Operations Supervisor

    Legend Biotech USA - Raritan, NJ, United States

    Legend Biotech is seeking an Operations Supervisor (2nd Shift) as part of theTechnical Operationsteam based in Raritan, NJ.Role OverviewThe CAR-T Operations Supervisor is an exempt level position working within Technical Operations team, responsible for directing the daily production of a personalized cell therapy to support both clinical and commercial requirements in a sterile cGMP environment. Job duties will be performed within a team-based environment, on an assigned production shift schedule. ...

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  • 2 days ago

    Sr. Payroll Analyst

    Legend Biotech USA - Bridgewater, NJ, United States

    Legend Biotech is seeking aSr. Payroll Analystas part of the HR Operationsteam based in Bridgewater, NJ.Role OverviewThe Senior Payroll Analyst is responsible for the accurate and timely administration and processing of the U.S. biweekly payroll for exempt and non-exempt employees in Workday. This role manages day-to-day payroll activities, including pay- roll processing, time and absence administration, payroll reconciliations, reporting, audits, and issue resolution. The Senior Payroll ...

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  • 2 days ago

    Head of Global Supply Chain, Procurement & Sourcing

    Legend Biotech USA - Bridgewater, NJ, United States

    Legend Biotech is seeking a Head of Global Supply Chain, Procurement & Sourcingas part of the Technical Operationsteam based in Bridgewater, NJ.Role OverviewTheHead of Global Supply Chain, Procurement & Sourcingis the enterprise leader accountable for the end-to-end supply of products and materials, from supplier through manufacturing and distribution to the patient/customer. The role establishes and executes the global strategy for demand and supply planning, strategic sourcing, procurement, ...

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  • 2 days ago

    Head of Global Manufacturing Science & Technology

    Legend Biotech USA - Bridgewater, NJ, United States

    Legend Biotech is seeking a Head of Global Manufacturing Science & Technologyas part of the Manufacturing Science & Technologyteam based in Bridgewater, NJ.Role OverviewThe Head of Global Manufacturing Science & Technology (MSAT)is the enterprise technical leader responsible for ensuring the robustness, scalability, capability, and continuous improvement of manufacturing processes across the product lifecycle. The role establishes the global MSAT strategy and provides technical leadership from ...

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  • 3 days ago

    IT Project Coordinator

    Legend Biotech USA - Bridgewater, NJ, United States

    Legend Biotech is seeking an IT Project Coordinator (Contractor)as part of the IT team based in Bridgewater, NJ. Role OverviewThe IT Project Coordinator supports the Global IT Project and Portfolio Management organization in planning, coordinating, and delivering small-scale, lower-complexity IT projects. The role also provides portfolio reporting, governance support, and administrative coordination across the global IT project portfolio. Working closely with project and program managers, ...

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  • 4 days ago

    Senior HRIS Analyst, Data Governance & Change Control

    Legend Biotech USA - Bridgewater, NJ, United States

    Legend Biotech is seeking a Senior HRIS Analyst, Data Governance & Change Controlas part of the Human Resources Operationsteam based in Bridgewater, NJ.Role OverviewThe Senior HRIS Analyst, Data Governance & Change Control is responsible for ensuring the accuracy, integrity, security, and appropriate use of HR data across the organization. This role supports data-driven decision-making by maintaining strong data governance practices, delivering reliable HR reporting and analytics, administering ...

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  • 6 days ago

    QC Stability Coordinator (Intern)

    Legend Biotech USA - Somerset, NJ, United States

    Legend Biotech is seeking a QC Stability Coordinatoras part of the Technical Developmentteam based in Somerset, NJ.Role OverviewLegend Biotech is seeking an Intern as part of the Analytical Development team based in Somerset, NJ to assist in the planning, execution, and documentation of stability studies to support pipelines. This role provides hands- on experience in laboratory operations, stability data trending, documentation, and compliance with regulatory guidelines. Key ResponsibilitiesOversee ...

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  • 6 days ago

    Sr. Manager US Payroll

    Legend Biotech USA - Bridgewater, NJ, United States

    Legend Biotech is seeking a Sr. Manager US Payrollas part of the HR Operations& Complianceteam based in Bridgewater, NJ. Role OverviewThe Senior Manager, US Payroll is responsible for leading the end-to-end payroll function for US, ensuring the accurate, timely, and compliant processing of multi-state payroll for all employees. This role provides strategic leadership and end-to-end operational ownership of U.S. payroll operations, ensuring the accurate, timely, and compliant processing ...

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  • 10 days ago

    Information Security Operations Analyst

    Legend Biotech USA - Somerset, NJ, United States

    Legend Biotech is seeking an Information Security Operations Analystas part of the Information Technologyteam based in Somerset, NJ. Role OverviewThe Information Security Operations Analyst is a key member of the Information Security Office, responsible for operating, tuning, and monitoring the company's security technology stack. The Analyst detects, triages, contains, and reports on security events; manages vulnerability, email, endpoint, network, and identity security controls; delivers ...

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  • 10 days ago

    Associate Director, Global Scientific Communications, Medical Affairs

    Legend Biotech USA - United States, United States

    Legend Biotech is seeking an Associate Director, Global Scientific Communications, Medical Affairsas part of the Medical Affairs team based Remotely.Role OverviewLegend Biotech is seeking a strategic and detail-oriented Associate Director to join our Global Scientific Communications team within the Medical Affairs organization. This role, working closely with the Scientific Communications team, is responsible for the creation, management, and optimization of scientific content that supports ...

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